陈光村

个人简历/Personal resume

  2011年获得浙江大学生命科学学院理学博士学位，同年进入中国科学院苏州纳米技术与纳米仿生研究所纳米生物医学研究部任助理研究员，2015年起任副研究员，2022年起任研究员。

  主要从事近红外Ⅱ区荧光影像技术及其在干细胞再生医学和神经科学的应用研究。目前已在Adv Mater, JACS, Adv Funct Mater, Adv Sci等著名期刊上发表SCI论文50余篇。主持和参与国家自然科学基金面上项目、国家重点研发计划、中国科学院先导专项等项目10余项。入选中国科学院青年创新促进会优秀会员、江苏省六大人才高峰高层次人才，江苏省333高层次人才培养工程培养对象，作为主要完成人获2017年度江苏省科学技术一等奖，2022年度中国分析测试协会科学技术奖（CAIA奖）特等奖，担任Materials Today Bio杂志编委。

研究方向/Research direction

  1. 近红外荧光探针及其在细胞功能和神经活动监测中的应用；

  2. 功能蛋白的设计及其细胞命运调控应用；

  3. 神经功能外场调控及神经再生修复。

招生信息/Enrollment information

  生物学、材料学、化学

论文专著/The monograph

近年来代表性文章： 

  1. Dehua Huang#, Xue Yang#, Zhao Peng#, Hongqiang Yin*, Yongyang Liu, Yejun Zhang, Chunyan Li, Guangcun Chen*, and Qiangbin Wang*. Multichannel-optical imaging for in vivo evaluating the safety and therapeutic efficacy of stem cells in tumor model in terms of cell tropism, proliferation and NF-κB activity. Biomaterials, 2024, 122510.

  2. Dehua Huang, Qianwu Wang, Yuheng Cao, Hongchao Yang, Meng Li, Feng Wu, Yejun Zhang, Guangcun Chen*, and Qiangbin Wang*, Multiscale NIR-II imaging-guided brain-targeted drug delivery using engineered cell membrane nanoformulation for Alzheimer's disease therapy. ACS Nano, 2023, 17, 5033-5046.

  3. Dehua Huang, Yuheng Cao, Xue Yang, Yongyang Liu, Yejun Zhang, Chunyan Li, Guangcun Chen*, Qiangbin Wang*. A nanoformulation-mediated multifunctional stem cell therapy with improved beta-amyloid clearance and neural regeneration for Alzheimer's disease. Adv. Mater., 2021, 33, 2006357.

  4. Guangcun Chen*, Yuheng Cao, Yanxing Tang, Xue Yang, Yongyang Liu, Dehua Huang, Yejun Zhang, Chunyan Li, and Qiangbin Wang*. Advanced near-infrared light for monitoring and modulating the spatiotemporal dynamics of cell functions in living systems. Adv. Sci., 2020, 7, 1903783.

  5. Chunyan Li#, Guangcun Chen#, Yejun Zhang, Feng Wu, Qiangbin Wang*. Advanced fluorescence imaging technology in the near-infrared-II window for biomedical applications. J. Am. Chem. Soc., 2020, 142, 14789-14804.

  6. Dehua Huang, Suying Lin, Qianwu Wang, Yejun Zhang, Chunyan Li, Rui Ji, Mao Wang, Guangcun Chen*, and Qiangbin Wang*. A NIR-Ⅱ fluorescence/dual bioluminescence multiplexed imaging for in vivo visualizing the location, survival and differentiation of transplanted stem cells. Adv. Funct. Mater., 2019, 29, 1806546.

  7. Guangcun Chen*, Yejun Zhang, Zhao Peng, Dehua Huang, Chunyan Li, Qiangbin Wang*. Glutathione-capped quantum dots for plasma membrane labeling and membrane potential imaging. Nano Res., 2019, 12, 1321-1326.